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Solute | TMS Resource Portal

Welcome to TMS Solutions' resource portal, Solute, where you will find the latest informative articles about mental health, neuromodulation techniques, and TMS.

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Aug 17, 2022 4:08:00 PM

Brain Stimulation and Other Biological Non-Pharmacological Interventions in Mental Disorders: An Umbrella Review [Review]

SOURCE: Neuroscience & Biobehavioral Reviews. 139:104743, 2022 Aug.

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Jun 30, 2022 3:46:00 PM

Inducing Cortical Plasticity to Manipulate and Consolidate Subjective Time Interval Production

SOURCE: Neuromodulation. 25(4):511-519, 2022 Jun.

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May 21, 2022 11:12:00 AM

A Case Series of Repetitive Transcranial Magnetic Stimulation in the Treatment of Major Depression During Pregnancy

SOURCE: Brain Stimulation. 15(2):373-375, 2022 Mar-Apr.

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Apr 10, 2022 3:39:00 PM

Corticomotor Plasticity as a Predictor of Response to High Frequency Transcranial Magnetic Stimulation Treatment for Major Depressive Disorder

SOURCE: Journal of Affective Disorders. 303:114-122, 2022 04 15.

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Feb 9, 2022 5:21:00 PM

Systematic Review of Preservation TMS That Includes Continuation, Maintenance, Relapse-Prevention, and Rescue TMS [Review]

Source: Journal of Affective Disorders. 296:79-88, 2022 01 01.

Wilson S; Croarkin PE; Aaronson ST; Carpenter LL; Cochran M; Stultz DJ;
Kozel FA


BACKGROUND: A dearth of evidence-based information exists to guide the delivery of transcranial magnetic stimulation (TMS) after a successful acute course of treatment for Major Depressive Disorder.

METHODS: To provide guidance for clinicians, existing literature focused on "preservation TMS" was systematically reviewed and synthesized. Preservation TMS was defined as TMS used to sustain a clinical response after a successful acute course of treatment and included reports using the terms maintenance, continuation, relapse prevention, or rescue TMS. The review protocol was registered on Open Science Framework and reported following PRISMA guidelines. Data were abstracted by two authors and discrepancies were resolved by a third author. Primary outcome measures focused on clinical efficacy. The evaluated studies were graded using the Levels of Evidence criteria published by the Oxford Centre for Evidence-Based Medicine.

RESULTS: The search included 536 abstracts and 16 additional papers, from which 63 full articles were screened. Data were abstracted from 30 qualifying sources (N=1,494) including 4 randomized controlled trials (one sham controlled), 14 open trials, and 12 case series. Overall, the quality of existing literature was low regarding efficacy but provided clear support for effectiveness and safety across a range of preservation TMS protocols based on mostly uncontrolled studies.

CONCLUSIONS: Existing literature suggests that preservation TMS protocols significantly vary and are mostly supported by open trials and case series. Due to a lack of effective alternatives, preservation TMS will likely be required for certain patients who respond to acute TMS therapy. More studies of preservation TMS are critically needed.

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