Solute | TMS Resource Portal

Welcome to TMS Solutions' resource portal, Solute, where you will find the latest informative articles about mental health, neuromodulation techniques, and TMS.

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Dec 12, 2022 1:25:00 PM

Non-Invasive Brain Stimulation for Treating Psychiatric Symptoms in Parkinson's Disease: A Systematic Review and Meta-Analysis [Review]

SOURCE: Journal of Clinical Neuroscience. 106:83-90, 2022 Dec.

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Oct 26, 2022 4:29:00 PM

Non-Invasive Transcranial Brain Modulation for Neurological Disorders Treatment: A Narrative Review [Review]

SOURCE: Life Sciences. 307:120869, 2022 Oct 15.

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Sep 13, 2022 4:59:00 PM

A Causal Role for the Human Subthalamic Nucleus in Non-Selective Cortico-Motor Inhibition

SOURCE: Current Biology. 32(17):3785-3791.e3, 2022 Sep 12.

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Sep 9, 2022 1:07:00 PM

The Cerebellum is Involved in Motor Improvements After Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease Patients

SOURCE: Neuroscience. 499:1-11, 2022 Sep 01.

AUTHORS: Wen X; Chi S; Yu Y; Wang G; Zhang X; Wang Z; Gesang M; Luo B

ABSTRACT: Accumulating evidence indicates that repetitive transcranial magnetic stimulation (rTMS) ameliorates motor symptoms in patients with Parkinson's disease (PD); however, patients' responses to rTMS are different. Here, we aimed to explore neural activity changes in patients with PD exhibiting different responses to high-frequency rTMS treatments using functional magnetic resonance imaging (fMRI). We treated 24 patients with PD using 10-session rTMS (10 Hz) over the supplementary motor area (SMA) for 10 days. Resting-state functional magnetic resonance imaging (rs-fMRI), the Unified Parkinson's Disease Rating Scale Part III (UPDRS-III) and other neuropsychological scales were performed at the baseline and endpoint of rTMS treatment. The changes in the fractional amplitude of low-frequency fluctuation (fALFF) were calculated. Significant improvements were observed in motor symptoms, especially in the sub-symptoms of
bradykinesia. All the participants were subsequently stratified into responders and non-responders according to the UPDRS-III reduction. We identified increased fALFF values in the left Crus II of the cerebellar hemisphere and bilateral thalamus as responsive signs to rTMS. Furthermore, the motor response to rTMS over the SMA, measured by the reduction in UPDRS-III and bradykinesia scores, was positively associated with increased fALFF values in the left Crus2 of cerebellar hemisphere,
left lobule VIIB of cerebellar hemisphere, right lobule VI of the cerebellar hemisphere, and the right postcentral gyrus. These findings provide evidence for the involvement of cerebellar activity in the motor response to rTMS treatment.

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Sep 6, 2022 10:44:00 AM

Motor Cortical Plasticity and its Correlation With Motor Symptoms in Parkinson's Disease

SOURCE: eNeurologicalSci. 29 (no pagination), 2022. Article Number: 100422.

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