Solute | TMS Resource Portal

Welcome to TMS Solutions' resource portal, Solute, where you will find the latest informative articles about mental health, neuromodulation techniques, and TMS.

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Dec 10, 2022 1:16:00 PM

Motor Cortex Excitability in Chronic Low Back Pain

SOURCE: Experimental Brain Research. 240(12):3249-3257, 2022 Dec.

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Oct 21, 2022 4:00:00 PM

Resting-State Functional Connectivity Predicts Motor Cortex Stimulation-Dependent Pain Relief in Fibromyalgia Syndrome Patients

SOURCE: Scientific Reports. 12(1):17135, 2022 Oct 12.

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Sep 21, 2022 1:29:00 PM

Imagined Paralysis Reduces Motor Cortex Excitability

SOURCE: Psychophysiology. 59(10):e14069, 2022 Oct.

AUTHORS: Hartmann M; Falconer CJ; Kaelin-Lang A; Muri RM; Mast FW

ABSTRACT: Mental imagery is a powerful capability that engages similar neurophysiological processes that underlie real sensory and motor experiences. Previous studies show that motor cortical excitability can increase during mental imagery of actions. In this study, we focused on possible inhibitory effects of mental imagery on motor functions. We assessed whether imagined arm paralysis modulates motor cortical excitability in healthy participants, as measured by motor evoked potentials (MEPs) of the hand induced by near-threshold transcranial magnetic stimulation (TMS) over the primary motor cortex hand area. We found lower MEP amplitudes during imagined arm paralysis when compared to imagined leg paralysis or baseline stimulation without paralysis imagery. These results show that purely imagined bodily constraints can selectively inhibit basic motor corticospinal functions. The results are discussed in the context of motoric embodiment/disembodiment.

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Sep 16, 2022 1:17:00 PM

The Role of the Primary Motor Cortex in Motor Imagery: A Theta Burst Stimulation Study

SOURCE: Psychophysiology. 59(10):e14077, 2022 Oct.

AUTHORS: Barhoun P; Fuelscher I; Do M; He JL; Cerins A; Bekkali S; Youssef GJ; Corp D; Major BP; Meaney D; Enticott PG; Hyde C

ABSTRACT: While mentally simulated actions activate similar neural structures to overt movement, the role of the primary motor cortex (PMC) in motor imagery remains disputed. The aim of the study was to use continuous theta burst stimulation (cTBS) to modulate corticospinal activity to investigate the putative role of the PMC in implicit motor imagery in young adults with typical and atypical motor ability. A randomized, double blind, sham-controlled, crossover, offline cTBS protocol was applied to 35 young adults. During three separate sessions, adults with typical and low motor
ability (developmental coordination disorder [DCD]), received active cTBS to the PMC and supplementary motor area (SMA), and sham stimulation to either the PMC or SMA. Following stimulation, participants completed measures of motor imagery (i.e., hand rotation task) and visual imagery (i.e., letter number rotation task). Although active cTBS significantly reduced corticospinal excitability in adults with typical motor ability, neither task performance was altered following active cTBS to the PMC or SMA, compared to performance after sham cTBS. These results did not differ
across motor status (i.e., typical motor ability and DCD). These findings are not consistent with our hypothesis that the PMC (and SMA) is directly involved in motor imagery. Instead, previous motor cortical activation observed during motor imagery may be an epiphenomenon of other neurophysiological processes and/or activity within brain regions involved in motor imagery. This study highlights the need to consider multi-session theta burst stimulation application and its neural effects when probing the putative role of motor cortices in motor imagery.

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Sep 4, 2022 5:45:00 PM

Measuring Contralateral Silent Period Induced by Single-Pulse Transcranial Magnetic Stimulation to Investigate M1 Corticospinal Inhibition

SOURCE: Journal of Visualized Experiments. (186), 2022 Aug 23.

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