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Solute | TMS Resource Portal

Welcome to TMS Solutions' resource portal, Solute, where you will find the latest informative articles about mental health, neuromodulation techniques, and TMS.

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Aug 7, 2022 3:09:00 PM

Mapping Inter-Individual Functional Connectivity Variability in TMS Targets for Major Depressive Disorder

SOURCE: Frontiers in Psychiatry. 13 (no pagination), 2022. Article Number: 902089.

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Jun 6, 2022 3:01:00 PM

Non-Invasive Brain Stimulation Interventions for Treating Clinical and Sub-Clinical Eating Disorders: A Meta-Analysis of Randomized Controlled Trials and Nonrandomized Studies

SOURCE: Psychiatry Research. 313:114592, 2022 07.

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May 28, 2022 4:46:00 PM

Neuromodulation and Eating Disorders [Review]

SOURCE: Current Psychiatry Reports. 24(1):61-69, 2022 01.

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Apr 19, 2022 1:20:00 PM

'My Dad was Like "It's Your Brain, What Are You Doing?"': Participant Experiences of Repetitive Transcranial Magnetic Stimulation Treatment in Severe Enduring Anorexia Nervosa

SOURCE: European Eating Disorders Review. 30(3):237-249, 2022 May.

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Dec 14, 2021 5:20:00 PM

Reduction of Impulsivity in Patients Receiving Deep Transcranial Magnetic Stimulation Treatment for Obesity

Source: Endocrine. 74(3):559-570, 2021 12.

Authors: Luzi L; Gandini S; Massarini S; Bellerba F; Terruzzi I; Senesi P; Macri C; Ferrulli A

Abstract
PURPOSE: Aims of the present study were to investigate a wide array of psychological symptoms through validated psychometric tests, before and after 5 weeks of deep Transcranial Magnetic Stimulation (dTMS) in individuals with obesity, and to identify possible relationships with neuroendocrine parameters.

METHODS: Forty-five patients with obesity (33 F, 12 M; age 48.8 +/- 9.9 years; body wt 97.6 +/- 14.2 Kg; BMI 36.2 +/- 4.2) were randomized into two groups: 26 received high frequency (HF) dTMS and 19 Sham stimulation for 5 weeks. At baseline and after the 5-week treatment, all patients underwent the following psychometric evaluations: Food Cravings Questionnaire-Trait (FCQ-T) and its subscales, Barratt Impulsiveness Scale-11 (BIS-11), State and Trait Anxiety Inventory (STAI-y1 and
STAI-y2), and Beck Depression Inventory (BDI). Hormonal and neuroendocrine
markers were assessed at the first and last dTMS session.

RESULTS: By adjusting for baseline variables and treatment arms, a significant decrease in body wt and BMI was found in HF group, both with univariate (p = 0.019) and multivariate analyses (p = 0.012). Impulsivity significantly decreased in HF group, both with univariate (p = 0.031) and multivariate analyses (p = 0.011). A positive association between the impulsivity score change and the leptin level variation (p = 0.031) was found.

CONCLUSION: The decrease of impulsivity together with the BMI reduction in individuals with obesity, treated with real stimulation, suggests that impulsivity may be a risk factor for obesity. Treatment with dTMS revealed to be effective in reducing both BMI and impulsivity by enhancing inhibitory capacity of Pre-Frontal Cortex

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