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Solute | TMS Resource Portal

Welcome to TMS Solutions' resource portal, Solute, where you will find the latest informative articles about mental health, neuromodulation techniques, and TMS.

Relevant Posts

Jul 6, 2022 11:41:00 AM

The Efficacy and Safety of Transcranial Magnetic Stimulation in Treatment-Resistant Bipolar Depression

SOURCE: Psychiatria Danubina. 34(2):236-244, 2022 Summer.

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Jun 13, 2022 2:34:00 PM

Treatment-Resistant Bipolar Depression: Concepts and Challenges for Novel Interventions [Review]

SOURCE: Revista Brasileira de Psiquiatria. 44(2):178-186, 2022 Mar-Abr.

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May 13, 2022 2:10:00 PM

Could Bipolar Depressed Patients Respond Better to rTMS than Unipolar Depressed Patients? A Naturalistic, Observational Study [Review]

SOURCE: Psychiatry Research. 312:114545, 2022 Jun.

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Feb 14, 2022 2:57:00 PM

Predictors of Clinical Response After rTMS Treatment of Patients Suffering From Drug-Resistant Depression

Source: Transl Psychiatry Psychiatry. 11(1):587, 2021 11 15.

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Dec 3, 2021 4:48:00 PM

Intermittent Theta-Burst Stimulation TMS Increases GABA in the Medial Prefrontal Cortex: A Preliminary Sham-Controlled Magnetic Resonance Spectroscopy Study in Acute Bipolar Depression

Source: Frontiers in Psychiatry. 12 (no pagination), 2021. Article Number: 665402.

Date of Publication: 11 May 2021.

Authors: Diederichs C.; DeMayo M.M.; Cole J.; Yatham L.N.; Harris A.D.; McGirr A.

Abstract
Background: Magnetic resonance spectroscopy (MRS) has been used to identify gamma-aminobutyric acid (GABA) alterations in mood disorders, particularly in the medial prefrontal cortex (mPFC) where decreased concentrations have been associated with anhedonia. In major depressive disorder (MDD), prior work suggests that repetitive transcranial magnetic stimulation (rTMS) increases mPFC GABA concentrations proportional to antidepressant response. To our knowledge, this has not been examined in acute bipolar depression.

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