Plewnia C; Schroeder PA; Wolkenstein L. Institution Plewnia, Christian. Department of Psychiatry and Psychotherapy, Neurophysiology & Interventional Neuropsychiatry, University of Tubingen, D-72076 Tubingen, Germany. Electronic address: firstname.lastname@example.org . Schroeder, Philipp A. Department of Psychiatry and Psychotherapy, Neurophysiology & Interventional Neuropsychiatry, University of Tubingen, D-72076 Tubingen, Germany. Wolkenstein, Larissa. Department of Clinical Psychology, Universi ty of Tubingen, D-72076 Tubingen, Germany.
Targeting the biased brain: non-invasive brain stimulation to ameliorate cognitive control. Comments Comment in: Lancet Psychiatry. 2015 Jul;2(7):585-6; PMID: 2 6303544
Source: The Lancet. Psychiatry. 2(4):351-6, 2015 Apr.
Abstract: Non-invasive brain stimulation has become important for the in vestigation of healthy and impaired neuronal functioning. Moreover, no n-invasive brain stimulation has emerged as a new means of psychiatric treatment, alt hough the mechanisms of action are still not understood and the opt imal mode of application is still under development. Dysfunctional cognit ive control is a central characteristic of various psychiatric disorders an d is associated with dysregulations of prefrontal cortex activity an d biased information processing. With non-invasive brain stimulation , enhancement and reduction of prefrontal cortex activity were shown to amel iorate and impair cognitive control, respectively. These findings sugg est a neurocognitive mechanism of therapeutic effects and that non-inv asive brain stimulation can be combined with training to target dysfunctional cognitive control and related clinical symptomatology. Nevert heless, the intra-individual and inter-individual diversity of neuro cognitive processes, the multiplicity of possible stimulation parameter s, and the complexity of interactions between those factors pose considerab le challenges for interpretation of these findings and their cli nical application.
Copyright © 2015 Elsevier Ltd. All rights reserved.
Publication Type: Journal Article. Research Support, Non-U.S. Gov't.