Neurostimulation for Depression in Epilepsy. [Review]

TITLE
Neurostimulation for Depression in Epilepsy. [Review]

SOURCE
Epilepsy & Behavior. 88S:25-32, 2018 11.

AUTHORS
Conway CR; Udaiyar A; Schachter SC.

ABSTRACT
Epilepsy is often associated with co-morbid psychiatric illnesses that can significantly impact its long-term course. The most frequent of these psychiatric co-morbidities is major depressive disorder, which affects an estimated 40% of patients with epilepsy. Many patients are underdiagnosed or undertreated, yet managing their mood symptoms is critical to improving their outcomes. When conventional psychiatric treatments fail in the management of depression, neuromodulation techniques may offer promise, including electroconvulsive therapy (ECT), vagus nerve stimulation (VNS), and repetitive transcranial magnetic stimulation (rTMS), as discussed in this review. “This article is part of the Supplement issue Neurostimulation for Epilepsy.”