Delayed effect of repetitive transcranial magnetic stimulation (rTMS) on negative symptoms of schizophrenia: Findings from a randomized controlled trial.




Curated By TMS Solutions on Mar 15, 2017 3:31:00 PM
Curated By TMS Solutions

 

Authors:

Li Z; Yin M; Lyu XL; Zhang LL; Du XD; Hung GC. Institution Li, Zhe. Department of Psychiatry, Suzhou Psychiatry Hospital, Suzhou, China. Yin, Ming. Department of Psychiatry, Suzhou Psychiatry Hospital, Suzho u, China. Lyu, Xiao-Li. Department of Psychiatry, Suzhou Psychiatry Hospital, Suzhou, China. Zhang, Lan-Lan. Department of Psychiatry, Suzhou Psychiatry Hospital, Suzhou, China. Du, Xiang-Dong. Department of Psychiatry, Suzhou Psychiatry Hospital, Suz hou, China. Electronic address: xiangdong-du@163.com . Hung, Galen Chin-Lun. Department of Psychiatry, Taipei City Psychiat ric Center, Taipei City Hospital, Taipei, Taiwan; Department of Public Health, School of Medicine, National Yang Ming University, Taipei, Taiwan. Electronic address: galenhung@tpech.gov.tw .

Title:

Delayed effect of repetitive transcranial magnetic stimulation (rTMS) on negative symptoms of schizophrenia: Findings from a randomized controlled trial.

Source:

Psychiatry Research. 240:333-5, 2016 06 30.

Abstract:

Evidence is inconsistent regarding the effect of repetitive transcranial magnetic stimulation (rTMS) on negative symptoms of schizophrenia. In this study, 47 patients were randomized to receive either active rTMS over left dorsolateral prefrontal cortex (n=25) or sham stimulation (n=22). Negative symptoms were assessed with the Scale for the Assessment of Negative Symptoms (SANS) at baseline, 4 weeks and 8 weeks. At 4 weeks, there was no difference in SANS scores between 2 groups. By 8 weeks, patients with active rTMS had significantly reduced SANS score than controls. Our findings suggest a delayed effect of rTMS on negative symptoms.

Copyright © 2016 Elsevier Ireland Ltd. All rights reserved. Publication Type Journal Article. Randomized Controlled Trial. Research Support, Non-U.S. Gov't.

Topic of this Article:

Topics: Schizophrenia, rTMS


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