Klomjai W; Katz R; Lackmy-Vallee A. Institution Klomjai, Wanalee. Faculty of Physical Therapy, Mahidol University, 73170 Nakonpathom, Thailand. Katz, Rose. UPMC Universite Paris 06, CNRS, Inserm, laboratoire d'imagerie biomedicale, Sorbonne universites, 75013 Paris, France; Service de medecine physique et readaptation, groupe hospitalier Pitie-Salpetriere, AP-HP, France. Lackmy-Vallee, Alexandra. UPMC Universite Paris 06, CNRS, Inserm, laboratoire d'imagerie biomedicale, Sorbonne universites, 75013 Paris, France. Electronic address: email@example.com .
Basic principles of transcranial magnetic stimulation (TMS) and repetitive TMS (rTMS). [Review]
Source: Annals of Physical & Rehabilitation Medicine. 58(4):208-13, 2015 Sep.
Abstract: Transcranial magnetic stimulation (TMS) and repetitive TMS (rTMS) are indirect and non-invasive methods used to induce excitability chan ges in the motor cortex via a wire coil generating a magnetic field that passes through the scalp. Today, TMS has become a key method to investi gate brain functioning in humans. Moreover, because rTMS can lead to long-lasting after-effects in the brain, it is thought to be able to induce plast icity. This tool appears to be a potential therapy for neurological and psychiatric diseases. However, the physiological mechanisms underlying the effects induced by TMS and rTMS have not yet been clearly identified. The purpose of the present review is to summarize the main knowledge available for TMS and rTMS to allow for understanding their mode of action and t o specify the different parameters that influence their effects. This review takes an inventory of the most-used rTMS paradigms in clinical research and exhibits the hypotheses commonly assumed to explain rTMS after-effects.
Copyright © 2015 Elsevier Masson SAS. All rights reserved.
Publication Type: Journal Article. Research Support, Non-U.S. Gov't. Review.