Intermittent theta burst stimulation over left BA10 enhances virtualreality-based prospective memory in healthy aged subjects.
Debarnot U; Crepon B; Orriols E; Abram M; Charron S; Lion S; Roca P; Oppenheim C; Gueguen B; Ergis AM; Baron JC; Piolino P.
Neurobiology of Aging. 36(8):2360-9, 2015 Aug.
Prospective memory (PM) refers to a complex cognitive ability that underpins the delayed execution of previously formulated intentions. PM performance declines early in normal aging and this process is accentuated in Alzheimer's disease. The left frontopolar cortex (BA10) has been consistently assigned a major role in PM functioning, but whether it can be noninvasively modulated to enhance PM performance in aged people has not been addressed so far. Here, we investigated the effects of modulatin